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Synovitis worsens, matrix components are destroyed, and apoptosis occurs as a result of oxidative stress-induced mitochondrial and nuclear DNA damage, lipid peroxidation, changes in cellular signal transduction and transcription, and epigenetic transcription factors (Marchev et al., 2017)

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Additionally, blood NAD + levels were significantly increased

albicans -mediated regulation of inflammatory, metabolic, and signaling pathways, as well as clarifying its complex interplay with the host, including the key molecular targets involved in immune evasion, microenvironment remodeling, and genotoxicity