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Furthermore, the optimization of erucamide analogs to enhance solubility and prolong in vivo half-life could potentially offer novel small-molecule-based therapies for AMD, retinitis pigmentosa and other neurovasculoglial degenerative diseases
Duzel A, Vlainic J, Antunovic M, Malekinusic D, Vrdoljak B, Samara M, Gojkovic S, Krezic I, Vidovic T, Bilic Z, Knezevic M, Sever M, Lojo N, Kokot A, Kolovrat M, Drmic D, Vukojevic J, Kralj T, Kasnik K, Siroglavic M, Seiwerth S, Sikiric P
A 2017 study showed that BPC-157 administration significantly reduced colonic inflammation markers and promoted mucosal healing in rodent colitis models through modulation of the NO system and reduction of oxidative stress
