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Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ

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DNA methylation also plays a role: hypermethylation of the ENPP2 promoter is associated with decreased ATX expression and poor prognosis in prostate adenocarcinoma (67), indicating that both transcriptional and post-transcriptional epigenetic events contribute to LPA metabolic dysregulation

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