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Eur J Med Res 30 , 267 (2025)

Despite these caveats, an increase in brain lactate in ME/CFS patients has been previously reported in 3T MRS investigations, in the ventricle CSF rather than in the brain tissue [14,15,16,17], and also in the ACC, similar to our study (the voxel in this study was placed in the area covering adjacent parts of our voxels) [13]