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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone

While B12 is naturally present in animal-based foods such as meat, fish, and dairy, many people struggle to get adequate amounts due to dietary restrictions, absorption issues, or certain medical conditions