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In PC, miR-124talin interaction exerts an antitumoral effect by reducing cell adhesion, migration, and invasion via integrins and the FAK/Akt pathway and an inverse correlation between these two players was found in clinical specimens [87]

While metformin's mechanism(s) of action remain controversial, current evidence indicates that metformin's most important effect in treating diabetes is to lower the hepatic production of glucose (as summarized in the top left box)

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Therefore, it plays a major role in the bodys ability to remove environmental pollutants, radiation, drugs, carcinogenic chemicals and heavy metals