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10.2147/DDDT.S386974 110 Ofosu-BoatengM.ShaikF.ChoiS.EkubanF

Deficiencies in NAD can impact a range of physiological functions, leading to numerous health issues

Therefore, the subsequent experiments were used to determine whether Sirt1 affected the nuclear translocation of Gli-1 and the expression levels of components of the Shh signaling pathway, such as Shh, Ptc-1, Smo and Gli-1