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Glucose metabolism via the PPP is essential for the generation of NADPH that is required for reductive biosynthetic reactions such as those of cholesterol biosynthesis, bile acid synthesis, steroid hormone biosynthesis, and fatty acid synthesis

GATM rs9806699 was reported to have a marginally protective effect on SIM (OR = 0.617, p = 0.024)

Recently, attention has focused on men recovering from Coronavirus disease-19 (COVID-19) infection as potential candidates for AOX therapy

58 A prominent limitation of Precision Nutrition (PN) is that most studies are observational rather than stemming from randomized controlled trials (RCTs) with evaluated clinical endpoints