Potential Interactions of AOD9604 with Fat Store Accumulation Another potential mechanism related to fat cells, which may be common between AOD9604 and hGH, is the apparent mitigation of acetyl-CoA carboxylase (ACC), an enzyme involved in fatty acid synthesis, thus potentially limiting new adipose tissue accumulation
This change to the structure extends the half-life to about 170 to 180 hours, which allows for dosing once a week
Chahardoli R, Saboor-Yaraghi AA, Amouzegar A, Khalili D, Vakili AZ, Azizi F (2019) Can Supplementation with Vitamin D Modify Thyroid Autoantibodies (Anti-TPO Ab, Anti-Tg Ab) and Thyroid Profile (T3, T4, TSH) in Hashimotos Thyroiditis
doi: 10.1007/BF02714149 9 CantoniO.SestiliP.PalombaL.GuidarelliA.CattabeniF.MurrayD