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MENK can intensify CD4 + T cell functions and secretion of cytokines by inducing dendritic cell maturation and regulating CD8 + T cells

Even though PE patients experience elevated blood pressure, their overall blood and plasma volumes are reduced 33,34 , and in such hypovolemic conditions, body fluids are distributed more into the tissue interstitium than into the vasculature, indicating capillary leakage 35

Although IL-1-mediated chondrocyte ferroptosis was observed in the aforementioned studies, the specific mechanisms are unclear