In humans, it has a very short half-life and is rapidly metabolized by liver enzyme CYP2A6 into cotinine and OH-Cotinine, which in turn can be utilized as clinical biomarkers to assess smoking-status 55

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The bottle, however, is problematic in that the sprayer screws onto the bottle but when I remove the cap, the sprayer gets stuck in the cap so effectively, I have to dab it on straight out of the bottle
The Substance Abuse and Mental Health Services Administration (SAMHSA) defines mental illness as any diagnosable mental, behavioral, or emotional disorder