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They are especially beneficial for individuals with B12 deficiencies, vegetarians, vegans, or those who have digestive issues that limit nutrient absorption

However, when compared to traditional orally administrated drugs, the pharmacokinetic properties of L-carnitine are complex, since it exhibits poor intestinal absorption and bioavailability, very high renal clearance, and uptake into tissues through a high affinity transporter [13]

Our goal is to move beyond the hype and facilitate a critical evaluation of the current scientific landscape, empowering informed decision-making in practice

Oral Supplementation and Systemic Drugs for Skin Aging: A Narrative Review