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Van Berkel, Wageningen University and Research, Netherlands Updates Copyright 2023 Smith and Moran

LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells

In contrast to our in vitro human model of the ischemic penumbra consisting in the combination of hiPSCs-derived neurons and rat astrocytes exposed to hypoxia and consequent low level of glucose, Bhatti and Frostig used an in vivo rat model in which the entire system of neurons, astrocytes, and blood flow is modified after permanent middle cerebral artery occlusion (pMCAo), which results in both hypoxic conditions and minimal glucose supply through major changes in collateral blood flow 36

De asemenea, este adesea asociat cu obezitatea i poate provoca simptome din cauza nivelului ridicat de hormoni masculini (androgeni)