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351 Nrf2 activation not only inhibits ROS, but also inhibits inflammation-related signaling molecules and the proliferation and migration of FLSs, thus alleviating RA synovitis effectively

[28] Hence, inhibitors of the LOX enzyme may be useful in preventing angiogenesis, tumor progression, and metastasis as well as treating other fibrotic disease involving remodeling of the extracellular matrix, including neurodegenerative and cardiovascular diseases