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This approach holds promise for investigating the reduction of dosage of drugs with severe side effects and developing research compounds tailored to specific disease states

In regard to DPI, we previously demonstrated that low micromolar concentrations effectively reduced tumor growth and metastasis in a MYCN-driven zebrafish model of NB, with low associated toxicity ( A limitation of this study is the discrepancy between the strong in vitro synergy of the MitoQ + DPI combination and its limited effectiveness in in vivo models of NB

doi: 10.1182/blood-2004-07-2599

Its research profile makes it especially relevant for studies focused on fat-cell pathway models, metabolic turnover, energy-balance signaling, methylation-adjacent biology, and body-composition pathway research