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doi: 10.1016/j.cellsig.2007.04.009

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Low B12 levels can cause a number of issues including: Low energy and stamina Sleep disturbances Immune system dysfunction Slow metabolism Mood changes Migraines and headaches Increased chances of heart disease Increased stroke risk Unsteady gait Low blood pressure There are many factors that can cause a drop in B12 levels or a need to increase B12 in the body

Further, we found that 500 M VPA and a standard menadione positive control for oxidative stress similarly (500 M VPA 1.919 0.2587 and 2.5 M menadione 1.869 0.2877-fold change from control) and significantly (500 M VPA vs control p = 0.0254