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Angiogenesis is the process where the body forms new blood vessels from pre-existing ones

The typical research protocol involves subcutaneous injection of 5-10 mg daily for 10-20 consecutive days, repeated in 4-6 month cycles

Studies examining long-term neuroplasticity, neuroprotection, or recovery from injury more frequently employ every-other-day or three-times-weekly schedules, recognizing that structural brain changes require time to develop and may benefit from pulsed rather than continuous stimulation

However, data suggest that SGLT2 inhibitors and GLP-1 receptor agonists remain underutilized in cardiology practice despite their established benefits (166)