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Description

HO-1 is a critical source of intracellular iron

CD1a selectively captures endogenous cellular lipids that broadly block T cell response

Used Annals of the New York Academy of Sciences 70% of the Immune System Resides in the Gut Approximately 70% of the immune system lives in the gut (gut-associated lymphoid tissue)

Ludewig B, Jaggi M, Dumrese T, Brduscha-Riem K, Odermatt B, Hengartner H, Zinkernagel RM (2001) Hypercholesterolemia exacerbates virus-induced immunopathologic liver disease via suppression of antiviral cytotoxic T cell responses