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Liu Y, Lu L, Yang H, Wu X, Luo X, Shen J, et al

The two mechanisms are complementary without overlap, making this a clean combination

Protection Against UV Damage Antioxidants neutralize free radicals and protect the skin from sun damage

The TRIUMPH-4 Phase 3 trial in obesity with knee osteoarthritis (Bays et al., NEJM 2025) reported 28.7% mean weight loss at 68 weeks at the 12 mg dose, plus a 75.8% reduction in WOMAC knee pain scores