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A subset of cultured cells expressed GLP- 1 receptor, and mice with a-cell specific GLP- 1 receptor knockout have mild glucose intolerance and higher glucagon secretion in response to glucose challenges than animals of the wild type, which may indicate that GLP- 1 directly affects this cell [69]

Poor growth rates and ill thrift may be seen in affected animals

Because BPC-157 is a gut-derived peptide, oral administration achieves meaningful local concentrations in the GI tract

This deficiency can result from conditions such as pernicious anemia, certain gastrointestinal disorders, or a diet low in animal products