Glutathione: At the heart of this IV therapy is glutathione, often referred to as the master antioxidant. Glutathione plays a critical role in neutralizing free radicals, supporting the immune system, and promoting detoxification
Conversely, severe acute oxidative stress killed GPX1/ mice, while wild-type mice supplemented with selenium survived normally
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Additionally, when pristine Raw264.7 cells were treated with varying concentrations (0, 3, 6, 12, 25, 50, 75, 100, and 150 g/mL) of PDA and PDA@Pt, the PDA alone did not exhibit a significant decline in cell viability, while the PDA@Pt group showed a minor reduction at high concentrations, suggesting that the nanodrug is virtually non-toxic to normal Raw264.7 cells (Fig