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The fact that any oral bioavailability exists for a 15-amino acid peptide is pharmacologically remarkable and warrants extensive research

doi: 10.1016/j.mrfmmm.2005.08.004

The effects of SSRIs on mortality in young rats may be mediated by SSRI-induced placental insufficiency rather than direct toxic effects on neonatal development and mortality ( p = 0.001) and CYP1A1 ( p = 0.002) were still observed between the study groups, although there was no significant effect on placental GST activity

Therefore, exploring the involvement of mitochondria in AP is crucial for understanding the disease mechanism and identifying potential therapeutic targets