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Also, there were significant improvements in cardiovascular and metabolic risk factors among patients treated with Qnexa [246]

(2005) Pancreatic islet-specific expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene deficient mice

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indicated that the peptide reduced over 50% of body weight gain in these laboratory models compared to controls, with heightened lipolytic activity observed within the adipose tissues of exposed rats, alongside an absence of notable disruptions in insulin sensitivity in these experimental settings