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In this group, the sole use of immunotherapy resulted in a mere 15.6% ORR and a progression-free survival (PFS) of just 3.4 months [121]

When amylin binds to these receptors, it triggers a cascade that makes you feel full sooner, slows the rate at which food leaves your stomach, and reduces the hedonic drive to eat, the pleasure-seeking component that makes high-calorie foods irresistible

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