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While TB500 alone increases fibroblast migration and BPC-157 alone improves the healing environment, the combination produces clearly better outcomes than either peptide on its own better cellular organization, superior collagen alignment, and improved mechanical strength

The results revealed that Neuroactive ligand-receptor interaction and Calcium signaling pathway were the primary mechanisms through which this combination exerted synergistic effects

The patients without a history of gastrectomy complained of pain in other intraoral mucosal areas (5/11, 45.5 %), dry mouth (3/11, 27.3 %), and dysgeusia (2/11, 18.2 %)