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Hypophagia induced by salmon calcitonin, but not by amylin, is partially driven by malaise and is mediated by CGRP neurons

(1984) [15], using enzyme immunoassay after intravenous administration, measured plasma half-lives of 4.0 0.7 minutes in dogs, 2.9 minutes in one monkey, and 2.0 0.54 minutes in rats

In some embodiments, any formulation or composition described herein has a pH that allows for sterilization (e.g., by filtration or aseptic mixing or heat treatment and/or autoclaving (e.g., terminal sterilization)) of a formulation or composition without degradation of the therapeutic agent