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The 2025 RCT: dermaroller plus copper peptide vs dermaroller alone The study followed patients with facial acne scars over 16 weeks using the Goodman and Baron qualitative and quantitative acne scar index

This could open up conversations about other symptoms or more robust treatment options, like menopause hormone therapy

The 2018 paper in Biochemical Pharmacology gave obese mice a membrane-permeable NNMT inhibitor and reported it significantly reduced body weight and white adipose mass, decreased adipocyte size, with the mice eating the same amount as before, and the authors noting the inhibitors did not impact total food intake nor produce any observable adverse effects [1]

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