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However, B12 shots can interact with some medications and are not recommended for people with certain conditions like kidney disorders

Aging athletes, especially those over the age of 60, are also at risk for deficiency with age-related atrophic gastritis, low stomach acid, and an inadequate amount of a certain protein needed to absorb B12 (intrinsic factor)

Some people notice improved energy within a few days, while others may take longer depending on their B12 levels

Moreover, some studies illustrated that some specific modifications of NP surface could mitigate the toxicity of NPs and make them tissue-specific (Lai et al., 2021)