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The NETs then activate factors XIIa and XIa of the coagulation cascade, which can cause microthrombi and secondary brain ischemia - and considerably secondary damage

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The authors harvested nasal olfactory mucosa or olfactory bulb, and prepared frozen samples of that, demonstrating the pathway of nucleic acid transfer using the system, focusing on the major nose-to-brain pathways involving olfactory nerve and trigeminal nerve