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While tirzepatide (Zepbound and Mounjaro) currently leads in terms of average weight loss in approved medications, CagriSema could become a strong competitor once Phase 3 results are released

Outcome (O): The primary outcomes assessed were cognitive improvements (e.g., changes in memory, attention, and executive functions) and emotional or functional enhancements (e.g., quality of life, social engagement, and daily functional abilities)

Optimise general joint health through evidence-based lifestyle measures: Maintain a healthy weight to reduce mechanical stress on weight-bearing joints Engage in regular low-impact exercise such as swimming, cycling, or walking to maintain joint mobility and strengthen supporting muscles Apply heat or cold therapy as appropriateheat for stiffness, cold for acute inflammation Follow a balanced diet with plenty of fruits, vegetables, and whole grains

Neuroscience, 169(2), 674-682