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Given that the mitochondrial membrane potential typically ranges from 140 to 180 mV, the TPP cation is able to accumulate several hundred-fold within the mitochondrial matrix, presenting a highly efficient targeting ability

For instance, an investigation explored the effects of moderate treadmill exercise in middle-aged female Wistar rats over 15 weeks

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Yilmaz M, Kantarjian H, Muftuoglu M, Kadia T, Konopleva M, Borthakur G, DiNardo C, Pemmaraju N, Short NJ, Alvarado Y, Montalban-Bravo G, Jurisprudenica C, Pike A, Ohanian M, Jabbour E, Garcia-Manero G, Ruvolo V, Ravandi F, Andreeff M , Daver N