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Fertilizer and irrigation requirements of tobacco vary with the variety being grown but generally, tobacco has a requirement of 40-80 kg per hectare of nitrogen, 80-90 kg per hectare of phosphorous and 50-110 kg per hectare of potassium

Its also quite expensive because its hard to handle

As of October 2024, [60] China [edit] Although China faces many tobacco-related health problems, with over 1.2 million tobacco-related deaths per year, the government has had a limited response

Although the evidence is not consistent, appropriate doses of vitamin B12, vitamin D, vitamin C, selenium, folic acid, and antioxidants such as carotenoids have shown a preventive effect in certain types of cancer