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In selenium therapy, this could involve adjusting Se dosages based on the patients genetic makeup, which influences how they metabolize and respond to Se

Enemas were also effective in 5 trials on over 250 children, but didnt have any added benefits to laxatives in another one on 100 children [11, 12, 13, 14, 15, 16]

Although various methods for whole genome amplification have been developed 12 , multiple displacement amplification (MDA) using phi29 DNA polymerase with random primers is most widely used due to its relative simplicity, reliability and applicability 6,13

A conservative approach using 0.25 mg daily for the first two weeks allows assessment of individual response before considering increases