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The nanomaterial suspension was ultrasonicated for 30 min in the dark, after which zeta potential, UV-visible absorption spectra, and particle size distribution were calculated using a Xetasizer Nano ZS90 (Malvern Instruments, Marburg, UK) [6]

Safety and efficacy are debated, with limited scientific evidence supporting their effectiveness

Additionally, WA still has substantial limitations, and truly potent ferroptosis inducers with high-quality pharmacokinetic and pharmacodynamic properties remain to be identified