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Research Background DSIP has been investigated in preclinical models for its proposed neuromodulatory roles, including effects on sleep architecture, stress response, and the hypothalamic-pituitary axis

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However, there are several issues with FMT as follows: biological mechanisms remain undescribed, donor stool will not always be available, risks and side effects remain unclear, and long-term safety data are extremely limited (Liu Y

Free Radic Biol Med 46 , 16331638, (2009)