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On the one hand, the large hydrophobic inducer-binding pocket in a canonical TetR regulator has been repurposed by the heme-regulated transporter regulator from L

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30 In addition, they compared N-acetylcysteine amide (NACA) with NAC in an animal model of RP and reported that mean photopic ERG b-wave amplitude was 50% higher (p=0.001) at all 3 stimulus intensities in NACA-treated versus NAC-treated mice, and more than 4-fold greater than controls

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